Assessment of Antidiabetic Potential and Phytochemical Profiling of Viscum album, a Traditional Antidiabetic Plant

The traditional antidiabetic plant Viscum album (V. album) was collected from the oak in wild at Maidan, Khyber District, of Pakistan, for assessment its potential and phytochemical profile. Lowering blood glucose level, antioxidant effect, lipids pro?le, liver function marker enzymes, kidney markers were evaluated extract glibenclamide treated groups, normal as well diabetic control groups. An elevated level (Cholesterol, TG, LDL), enzymes (ALT, AST, ALP), (bilirubin, creatinine, urea) observed alloxan-induced rats; however, a HDL decreased. Administration V. hydroalcoholic 28 days renovated significantly ( p < 0.05 ) all above biochemical parameters. SOD, CAT, GPX also considerably restored. In vitro, assay indicated that 2,000 µg/mL scavenges free radicals DPPH 68.4%, ABTS 69.5%, H2O2 50.6%. extracts revealed presence saponins, flavonoids, alkaloids, terpene, tannins, phenols, protein, amino acids, sterols, glycosides. has shown phenolic contents 421 ± 4.8 mg GAE/100 g d. w flavonoids content 127 1.4 equiv. Rut/100 w. findings this research recommend could be potent source natural constituents.